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عمومی::
کمپلکس سازگاری بافتی اصلی، کمپلکس سازگاری بافت اصلی
HLA is the human version of the major histocompatibility complex (MHC), a gene family that occurs in many species.
In humans, the MHC complex consists of more than 200 genes located close together on chromosome 6.
Humans have three main MHC class I genes, known as HLA-A, HLA-B, and HLA-C.
MHC class I proteins display these peptides to the immune system.
There are six main MHC class II genes in humans: HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQB1, HLA-DRA, and HLA-DRB1.،Examples of peptides usable for such a modification include suitable tag sequences (typically histidine tag or FLAG tag), peptides having amino acid sequences which can be recognized by a T-cell receptor (TCR) or a major histocompatibility complex (MHC), proteins derived from viruses or bacteria or peptides having sequences derived from such proteins.
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